Sea Legs chewable tablets have been specially formulated to provide effective relief for all the family whether travelling by car, plane, boat or coach from motion/sea sickness. Each tablet contains the active ingredient meclozine hydrochloride, which is a type of antihistamine. Meclozine works by blocking histamine receptors found in various places in the body, including an area in the brain known as the vomiting centre. Sea-legs tablets can help prevent travel sickness for up to 24 hours. Sea-legs tablets can be taken either an hour before travelling, or the evening before. This medicine can also be used if the feeling of sickness develops during a journey.